is the second episode of the fourth season of the medical drama series Grey's Anatomy .
George struggles with his guilt after admitting he loves Izzie, while Callie, as Chief Resident, is overwhelmed by her duties and her suspicions that George is cheating. [S4E2] Love/Addiction
Meredith's half-sister, Lexie, attempts to bond with Meredith, who remains resistant to having a relationship with her. is the second episode of the fourth season
The residents and interns treat victims of a massive apartment fire caused by a meth lab explosion. Alex Karev deals with a particularly difficult case involving a baby who suffered a stroke due to the meth lab environment. The residents and interns treat victims of a
Watch a recap of the episode's themes and major character developments here:
The episode explores various forms of "addiction"—from chemical dependency to toxic emotional attachments—as the staff at Seattle Grace Hospital treats victims of a massive apartment explosion. Main Plotlines