The name is an acronym for the four independent predictors it tracks:
If you are looking for or comparisons to other models like the IPI or NCCN-IPI , I can provide those details.
While the International Prognostic Index (IPI) is the standard, KBMP4 provides a more granular look at aggressive "Double-Hit" or "Double-Expression" lymphomas. The name is an acronym for the four
Changes in interim PET/CT scan results after 4 treatment cycles (specifically a decrease in SUVmax < 71%). Risk Stratification & Survival Rates
The model is a clinical scoring system used to predict the survival and prognosis of patients with de novo Diffuse Large B-cell Lymphoma (DLBCL) . High KBMP4 scores often signal that standard R-CHOP
High KBMP4 scores often signal that standard R-CHOP therapy may not be enough, potentially leading to more intensive consolidative strategies or clinical trials.
The model categorizes patients into three risk groups based on how many of these four parameters they meet: Risk Subgroup Criteria (Parameters met) Progression-Free Survival (PFS) Overall Survival (OS) 0 parameters Intermediate 1 or 2 parameters High-Risk 3 or more parameters The name is an acronym for the four
High proliferation index (Ki67 ≥ 70%) on immunohistochemistry. B (Bulky): Physical presence of a tumor mass ≥ 7.5 cm.