To buy OTC (Over-the-Counter) stocks on E TRADE, you must navigate a different fee structure and stricter order requirements compared to standard exchange-listed stocks. While E TRADE offers $0 commissions for US-listed stocks, . This fee may be reduced to $4.95 if you execute 30 or more trades per quarter. Step-by-Step Purchase Guide How To Buy Otc Stocks On Etrade - Process Street