: Should be avoided unless a strict benefit/risk assessment justifies it.
: The association is possible provided that specific recommendations (e.g., monitoring, dosage adjustment) are followed.
: Highlights a risk where no specific management is currently recommended other than clinical awareness. : Should be avoided unless a strict benefit/risk
: A specific working document compiled by hospital pharmacy services (Sarreguemines and Caen) specifically focusing on the "Contraindicated" level for clinical safety.
The "Contraindicated" level is the highest of the four official clinical severity grades and has an absolute character; it must not be transgressed due to frequent and severe clinical consequences. Essential Official Documents : A specific working document compiled by hospital
For real-time analysis of a specific prescription, you can also use professional tools like the . Thesaurus des interactions médicamenteuses - ANSM
: This is the primary reference guide used by healthcare professionals to identify absolute contraindications (CI), associations to be avoided (ASDEC), and precautions for use. Thesaurus des interactions médicamenteuses - ANSM : This
The ANSM classifies interactions into four increasing grades of importance:
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