In the Sewers, you must collect chess-themed electronic plugs to open the U-Area door.
No context provided, but the title you mentioned—"detonado-resident-evil-2-remake-pc-crackeado-modo-facilitado-e-padrao"—suggests you're looking for a comprehensive guide (detonado) for on PC, specifically covering both Assisted (Facilitado) and Standard (Padrão) modes. In the Sewers, you must collect chess-themed electronic
You need the Electronic Part (Detonator) from the Operations Room and a Battery from the S.T.A.R.S. Office. Solution is Woman, Bow, Snake. In the Sewers
He cannot enter the S.T.A.R.S. Office, the Save Rooms (usually), or the Clock Tower. the Save Rooms (usually)
Red rooms still have items to find; Blue rooms are cleared. This prevents backtracking for missed ammo.