Athena Heart [310] Page

It is intended to reduce the risk of hospitalization for AF. 3. Safety and Contraindications

The official FDA label outlines critical safety measures based on ATHENA data: : ATHENA HEART [310]

: The trial established dronedarone as a rhythm-control therapy specifically aimed at reducing clinical complications rather than just maintaining sinus rhythm. 2. Dronedarone (Multaq) Usage Guide It is intended to reduce the risk of hospitalization for AF

Stop other Class I or III antiarrhythmics (e.g., amiodarone, sotalol) before starting Multaq. Avoid strong (e.g., ketoconazole). ATHENA HEART [310]

: Contraindicated in patients with symptomatic heart failure or recent hospitalization for heart failure (NYHA Class IV or symptomatic Class II-III).