: Fluconazole , itraconazole , and voriconazole . 2. Polyenes
-(1,3)-D-glucan, a major polysaccharide responsible for maintaining the structural integrity of the cell wall, causing cell lysis. antifungal agent
: This blocks an early step in ergosterol biosynthesis, leading to a toxic buildup of squalene and depletion of ergosterol. Common Examples : Terbinafine. Antifungal Agents - StatPearls - NCBI Bookshelf - NIH : Fluconazole , itraconazole , and voriconazole
: This class targets the fungal cell wall rather than the membrane. They inhibit the enzyme -(1,3)-D-glucan synthase. Effect : This blocks the synthesis of and voriconazole . 2. Polyenes -(1
